Re: Human Papillomavirus Type 16 and 18 Variants: Race-Related Distribution and Persistence
نویسندگان
چکیده
منابع مشابه
Human papillomavirus type 16 E2 and E6/E7 variants.
OBJECTIVES Polymorphisms in human papillomavirus (HPV) type 16 have been shown to be related to geographic areas and are broadly classified as European (E), African (Af), Asian (As), or Asian-American (AA). Certain variants have been reported as being more likely to cause cervical disease; our objectives were to identify new HPV16 polymorphisms, to determine the linkage of the E2 and E6/E7 regi...
متن کاملHuman papillomavirus type 16 variants and risk of cervical cancer.
There are substantial data demonstrating that human papillomaviruses (HPVs) are the sexually transmitted etiologic agents of cervical cancer (1). HPV type 16 (HPV16) is the most common HPV type detected in tumors, accounting for 50% of cancers and their precursors, called high-grade squamous intraepithelial lesions (HSILs) (2). Preliminary studies (3–16) have suggested that variants of HPV16 ma...
متن کاملPresence of Human Papillomavirus -16 and -18 Among Women with Breast Cancer in Isfahan Province
Background: Various studies proposed virus infection is to be a possible cause of human breast cancer. However, the data argue the association between virus and cancer are inconsistent. This study was conducted to detect whether HPV-DNA is present in tissue samples of breast cancer in Isfahan province. Materials and Methods: Paraffin embedded formalin fixed specimens were prepared from 40 brea...
متن کاملDistribution of human papillomavirus types 16 and 18 variants in squamous cell carcinomas and adenocarcinomas of the cervix.
The distributions of human papillomavirus (HPV) types detected in cervical adenocarcinomas and squamous cell tumors differ. However, whether the distributions of intratypic HPV variants seen in these two histological forms of cervical disease differ is unknown. Our objective was to compare the distribution of HPV intratypic variants observed in squamous cell carcinomas (SCC) and cervical tumors...
متن کاملCorrelation of human papillomavirus type 16 and human papillomavirus type 18 e7 messenger RNA levels with degree of cervical dysplasia.
Infection with certain types of human papillomavirus (HPV) is a necessary event in the development of cervical carcinoma; however, not all women who become infected with HPV will progress to cancer. Much is known about the molecular influence of HPV E6 and E7 proteins on the malignant transformation. Little is known about the additional factors needed to drive the process. Quantitative real-tim...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2007
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djk136